Bright Instruments Limited is a privately owned business. They supply a quality range of cryostats, microtomes, freezing units and accessories to pathology, histopathology, immunology, life sciences, research and industrial testing & quality control laboratories world-wide.
5040 Rotary Microtome
The popular 5040 microtome is of rotary retracting, self-lubricating design and has a heavy cast alloy base and cutting arm. Its robust construction makes it accurate and incredibly reliable.
The use of fixed beryllium hinges means that all lateral motion is controlled and allows no slop or play that can be experienced in other, lesser designs which can result in ‘chatter’ and ‘thick and thinning’. Its pawl and ratchet wheel and head-advance design ensures absolute calibration for section thickness accuracy and repeatability.
Features of the 5040 Rotary Microtome
- Easy to use rotary retracting microtome with wide range of optional features
- Choice of advance/rewind handle positions
- Motor drive with zone control is available
- Of hard wearing construction and maintenance free
- Standard knife holder accepts most conventional knives
- Quick release feather blade holder can be fitted
- Specimen feed indicator
- Safety features include fitted knife guards and locking handwheel
Based on the long-established and reliable OTF/AS cryostat, the new OTF5000 brings the extensive range of Bright cryostats completely up to date. New styling coupled with improved user ergonomics, the latest blade systems in the ever-reliable and powerful 5040 microtome, a huge choice of options plus money-saving package deals make these cryostats absolutely unique.
They are suitable for an endless range of applications and, in the correct configuration, are capable of cutting a wide diversity of specimens from undecalcified bone to brain, resins, plastics and plant tissue, as well as more usual soft tissue. Allowing full anti-roll plate adjustment for perfect results coupled with long lasting temperature stability, the OTF5000 Cryostat can truly be described as complete.
OTF5000 Cryostat Microtome Features
- New contoured top for added operator comfort and usability
- Suitable for research and clinical operation
- 2 money-saving special packages availablet
- Uses solid knives or disposable blades including new lever release Feather blade holder
- Available in 2 different working heights
- Automatic evaporator defrost supplied as standard
- Non-urgent functions on side panel
- Long list of options and accessories
- Contains tried and tested 5040 rotary microtome
The Clini-RF is a new type of freezer designed to rapidly freeze specimens for sectioning or processing.
It has a lower chamber which can be filled with 3M’s Novec 7100, into which specimens can be immersed. 3M’s Novec is the only freezing liquid that can be used due to it being none inflammble. Alternatively, an aluminium block can be incorporated, into which a specimen holder or chuck can be fitted. The upper chamber is used as a short term storage area for specimens after they have been initially frozen in the lower chamber.
The Clini-RF eliminates the need to use potentially hazardous substances such as carbon dioxide and liquid nitrogen. In order to save power, the compressor for the lower chamber can be manually switched off when it is not required and the Clini-RF will run in a ‘standby’ mode with the upper chamber still running at -40ºC.
A seven day timing device is available as an optional feature to automate switching between the ‘standby’ and ‘operational’ modes. An additional optional feature is a variable temperature control for temperatures above -80ºC.
Features of the Clini-RF Laboratory Freezer
- Replaces liquid nitrogen freezing systems
- Replaces carbon dioxide freezing systems of all types
- Offers a distinct improvement in laboratory safety
- Easy to use, therefore little operator training is required
- Upper chamber available for storage at -40ºC
- Holds 3M’s Novec 7100 for immersion of specimens
- Typical tissue cooling rate of 0.5ºC/s
The 8000 retracting base sledge microtome offers the ultimate in versatility combined with strength, accuracy, reliability and, not least, safety.
Designed to meet the needs of the routine histology laboratory, the 8000 will also meet the more demanding requirements of the specialised unit where its versatility and wide range of accessories will guarantee that it becomes the first choice of the professional base sledge user.
The 8000 microtome is well suited to cutting a wide range of materials including bone, plastics, resins and wood as well as large area soft tissues and is the first of its kind to incorporate retraction on the return stroke.
Features of the 8000 Sledge or Sliding Microtome
- Easy to use base sledge retracting microtome complete with standard vice
- 60µm retraction on the return stroke prevents possible specimen damage
- Angled and slewable knife holder for greater versatility
- Accepts a range of knives and disposable blades
- Safety features include knife guards and low positioned operating handle
- Range of stages available
For some sectioning work, it is necessary to cool a specimen below room temperature. The Solid State Freezer can be fitted to most microtomes and will permit specimen cooling from ambient to -25ºC or lower, depending on conditions. The equipment consists of a cooling stage and a control unit. The cooling stage is best suited for operation with a base sledge microtome, but can be fitted to most rotary microtomes.
Features of the Solid State Freezer for Microtomes
- Turns a microtome into a freezing microtome
- Will fit most other manufacturers’ equipment
- Choice of two stage sizes
- Easy to defrost
- Many other uses around the laboratory where small area freezing is required
Capp ApS is a privately owned Danish manufacturing company that enjoys the reputation of a dependable supplier of liquid handling products all across the world due to its strong focus on providing innovative and user friendly global standard premium liquid handling Equipments.
Capp offers a wide range of high quality tips to fulfill the pipetting needs of research, diagnostics and analytical Laboratories.
Premium design – more than 25 years of expertise as a pipette manufacturer gives Capp the necessary know-how to select and design tips that match the expectations of the strictest customers:
Universal compatibility to the great majority of pipette brands on the market
Crystal clear clarity & Increment marks for convenience of use
Different lengths within the same volume range for different applications
Premium manufacturing – absolutely no compromise made on the quality parameters:
Superb quality, Swiss made injection molds
Clean-room facility to eliminate the risk of contamination
Certified RNase, DNase, DNA and Pyrogen free
Made from virgin polypropylene
Premium portfolio – different designs of tips within the same volume range to fit almost all pipettes available on the market:
Select from ExpellPlusTM low retention or ExpellTM standard (both of extremely high quality)
Options of bulk, racked, racked-sterile, reloads, racked-sterile-filtered and bulk-filtered tips
ExtractMe nucleic acid isolation kits, reagents, enzymes and educational kits are innovative porducts from DNA-Gdansk. LabConsulting.at offers a comprehensive range of molecular biology products Meeting with the highest standards for laboratory research.
ExtractMe Kits are available also online in LabShop online www.labshop-online.com
- Kits for nucleic acid isolation and purification from different sources
- Reagents for PCR techniques, including DNA polymerases, PCR enhancers, Master Mixes and deoxyribonucleotides
- RNA related products (eg. cDNA synthesis kits)
- Enzymes & recombinant proteins
- Educational kits in field of molecular biology, diagnostics and genetics designed to facilitate laboratory trainings
- DNA and protein ladders, agaroses
- PCR kits for detection of bacterial and fungal DNA (For Research Use Only)
Syngene is a division of the Synoptics Group, founded in 1985 by imaging experts from the University of Cambridge. At Syngene people live and breathe image analysis because products specifically around Gel Imager for gel documentation and fluorescence/chemiluminescence imaging are all they have ever focused on developing.
Basic gel doc Systems
Gel Imaging systems for entry-level and basic application use are developed . These systems are ideal for DNA/RNA fluorescence and 1D protein imaging. These systems are at the budget end of the market but deliver with no compromise on specification or performance. Basic systems are predominantly manually driven but when used with GeneSys image capture software ensure that the systems are easy to use.
Syngene, with its imaging expertise, has pioneered the development of automated gel documentation systems since 1985 to bring you world leading gel imaging systems. Within these ranges you’ll find the perfect gel doc system to suit your budget and the level of sophistication your fluorescence imaging demands.
Rapid DNA, RNA and protein gel imaging
You can use a G:BOX, PXi, InGenius, U:Genius or DigiGenius to rapidly visualise Ethidium bromide, GelRed™, GelGreen™ and dyes from the SYBR® range. You can perform accurate fluorescent protein gel imaging using SYPRO® and ProQ® dyes.
To visualise colourless spots or bands on a TLC (Thin Layer Chromatography) plate, you can either use a plate with a fluorescent indicator or view it under UV light or you can spray reagents onto the samples to colour them so that spots are visible in white light.
Using its extensive imaging expertise, Syngene has developed the G:BOX systems for automated imaging of TLC plates.
Advanced gel doc Systems
The advanced gel doc systems from Syngene cover a wider range of applications. These include DNA, 1D and 2D gels, chemiluminescence, coloured fluorescence and multi-plex applications. All systems feature high performing cameras with exceptional sensitivity thus ensuring high quality imaging. All systems are fully automated and application driven to enable the user to obtain quantitative results quickly and easily.
For your complex fluorescence imaging and chemiluminescence imaging, Syngene has designed the high performance G:BOX range. The G:BOX can be configured with a choice of high resolution cooled 16-bit cameras, as well as different lighting and filter options making it excellent for your rapid DNA/RNA imaging, as well as chemiluminescence Imaging.
Syngene, with its imaging expertise, has pioneered the development of chemiluminescent imaging systems with its GeneGnome product, designed specifically for easy set-up. The systems have a cooled CCD camera which reduces background noise that can occur electronically within the camera when using long exposure time. However, with Syngene’s advanced technology, even the most complex chemiluminescence imaging is possible.
Using a 2D electrophoresis gel in proteomics applications provides you with much higher levels of resolution than a 1D gel and often results in thousands of protein spots for you to analyse from a single 2D gel.
Syngene, with its imaging expertise, has developed high specification systems and software for challenging 2D electrophoresis gel imaging. Using either a G:BOX Chemi XT4, G:BOX Chemi XX6 or a G:BOX Chemi XX9 they can be fitted with correct filters and lighting to provide separation of high spot densities, guaranteeing you unrivalled 2D gel imaging accuracy.
We offer sensitive DNA/RNA stains like GelRed, DNA binding Dyes, CF dyes , Quantitation kits and antibody labeling kits from Biotium. Innovation is at the very heart of what they do every day. As a relatively small technology company, they understand the importance of innovation to their competitiveness and growth. The company devotes a significant amount of resources to research and development and intellectual property protection.
Their efforts have resulted in a growing number of granted and pending patents that cover a number of industry-leading technologies, including the following:
GelRed™ and GelGreen™ nucleic acid gel stains: highly sensitive DNA/RNA gel stains made safe by preventing dye penetration into cells
EvaGreen™ DNA-binding Dye: qPCR dye working on a novel “release-on-demand” DNA-binding mechanism; the only dye that works perfectly for both qPCR and highly sensitive melt curve Analysis
CF™ dyes: A series of 20 highly water soluble dyes with colors spanning the entire visible and near infrared spectra; designed for protein labeling using breakthrough chemistries to produce unrivaled performance in brightness and photostability
Mix-n-Stain™ Antibody Labeling Kits: A revolutionary protein labeling technology that allows anyone to optimally label an antibody , with or without the presence of BSA or gelatin, with one of our CF™ dyes or biotin in 30 minutes and ~100% yield.
NucView™ Caspase 3/7 Enzyme Substrate: A novel concept to detect caspase activity in live cells by releasing a cell nucleus-staining dye upon substrate cleavage
AccuClear™ and AccuBlue™ DNA Quantitation Kits: Kits with the lowest dsDNA detection limit and widest linear range in the market
PMA™ DNA Modification Agent: An essential reagent for selective detection of viable pathogens by qPCR